SOCS1 polyclonal antibody
产品名称： SOCS1 polyclonal antibody
英文名称： SOCS1 polyclonal antibody
产品编号： PAB0214
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SOCS1.
- Immunogen:
- A synthetic peptide corresponding to human SOCS1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.05% BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- SARS-CoV nucleocapsid protein induced apoptosis of COS-1 mediated by the mitochondrial pathway.
Zhang L, Wei L, Jiang D, Wang J, Cong X, Fei R.Artif Cells Blood Substit Immobil Biotechnol. 2007;35(2):237-53.
- 2.
- Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry.
Simmons G, Gosalia DN, Rennekamp AJ, Reeves JD, Diamond SL, Bates P.Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11876-81. Epub 2005 Aug 4.
- Entrez GeneID:
- 8651
- Gene Name:
- SOCS1
- Gene Alias:
- CIS1,CISH1,JAB,SOCS-1,SSI-1,SSI1,TIP3
- Gene Description:
- suppressor of cytokine signaling 1
- Omim ID:
- 603597
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq
- Other Designations:
- JAK binding protein,STAT induced SH3 protein 1,Tec-interacting protein 3,cytokine-inducible SH2 protein 1
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Birth Weight
- Cardiovascular Diseases
- Celiac Disease
- Diabetes Complications
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Edema
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Hepatitis C
- Insulin Resistance
- Leukemia